Institution: Bordeaux University; France

Laboratory/Department: Interdisciplinary Institute of Neuroscience, CNRS UMR 5297

Position: Professor of Cell Biology and Neuroscience

Research topic: Central sensitization to pain: mechanisms of neuronal hyperactivity in the spinal cord:

  • peptidergic regulation,
  • epigenetic regulation by miRNAs,
  • network regulation by descending inputs,
  • pain comorbidities with anxiety/inattention/impulsivity

Methodologies: morphological approaches (light and electron microscopy), molecular biology, viral tracing, electrophysiology recordings

3 significant publications:

  • Laffray S, Bouali-Benazzouz R, Papon MA, Favereaux A, Jiang Y, Holm T, Spriet C, Desbarats P, Fossat P, Le Feuvre Y, Decossas M, Héliot L, Langel U, Nagy F, Landry M. (2012) Impairment of GABAB receptor dimer by endogenous 14-3-3 in chronic pain conditions EMBO J. 3239-3251.
  • Letellier M, Elramah S, Mondin M, Soula A, Penn A, Choquet D, Landry M, Thoumine O, Favereaux A. (2014) MicroRNA miR-92a regulates translation and synaptic incorporation of GluA1 containing AMPA receptors during homeostatic scaling. Nature Neuroscience. 17(8):1040-1042. doi: 10.1038/nn.3762.
  • Radwani H, Lopez-Gonzalez M, Dobremez E, Eriksdottir E, Langel Ü, Favereaux A, Landry M[1], Fossat P2. Differential effect of L-type calcium channel subunits in pain transmission and pain sensitization. (2016) Phyiology (London), doi: 10.1113/JP272725.

Participation in the EMN-Online teaching:

  • S1 – Cellular Neurobiology/Physiology
  • S2 – Experimental approaches of Neurosciences
  • S3 – Cell communication and plasticity
  • Partners

  • partner_idex
    Excellence Initiative of the University of Bordeaux
  • partner_erasmus
    Erasmus+ Programme
  • partner_mns
    Mediterranean Neuroscience Society
  • partner_ibro
    International Brain Research Organization