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DE MARCHIS Silvia

DE MARCHIS Silvia

Professor of Cell and Tissue Biology and Developmental Neurobiology

Institution: University of Turin, Italy

Laboratory/Department : Life Sciences and Systems Biology; Neuroscience Institute Cavalieri Ottolenghi (NICO)

Research topic: Adult neurogenesis in the mammalian brain (SVZ-olfactory bulb and DG of the hippocampus); study of the cellular/molecular mechanisms underlying specification/proliferation/differentiation of adult neural stem/progenitor cells.

Methodologies: morphological approaches (widefield and confocal microscopy), basic cell/molecular techniques, microsurgery (cell transplantation; viral tracing).

Publications

  • Jongbloets BC, Lemstra S, Schellino R, Broekhoven MH, Parkash J, Hellemons AJ, Mao T, Giacobini P, van Praag H, De Marchis S, Ramakers GM, Pasterkamp RJ. Stage-specific functions of Semaphorin7A during adult hippocampal neurogenesis rely on distinct receptors. Nat Commun. 2017 Mar 10; 8:14666. doi: 10.1038/ncomms14666.
  • Schellino R, Trova S, Cimino I, Farinetti A, Jongbloets BC, Pasterkamp RJ, Panzica G, Giacobini P, De Marchis S, Peretto P. Opposite-sex attraction in male mice requires testosterone-dependent regulation of adult olfactory bulb neurogenesis. Sci Rep. 2016 Oct 26;6:36063. doi: 10.1038/srep36063.
  • Bovetti S., Bonzano S., Garzotto D., Giannelli S.G., Iannielli A., Armentano M., Studer M., De Marchis S. COUP-TFI controls activity-dependent tyrosine hydroxylase expression in adult dopaminergic olfactory bulb interneurons. Development 140, 4850-4859, 2013.

Participation in the EMN-Online teaching

  • S2 : Developmental Biology and Ageing